Selection Guide,Pharmaceutical intermediate Glu-Asp-Arg / pinealon peptide

The glu asp arg peptide, also known as H-Glu-Asp-Arg-OH or the EDR peptide, is a fascinating molecule with growing interest in scientific research. This tripeptide is fundamentally a short chain of amino acids linked together by peptide bonds. Specifically, it is composed of three distinct amino acids: L-glutamic acid, L-aspartic acid, and L-arginine, arranged in that precise sequence. This specific arrangement defines its unique chemical and biological properties.

The molecular formula for this peptide is C15H26N6O8, with a molecular weight of approximately 418.41 Daltons. Its structure, with the sequence Glu-Asp-Arg, positions it within a broader category of peptides that are being investigated for various biological functions. While the term peptide can encompass a vast range of molecules, glu asp arg peptide refers to this specific three-amino acid sequence.

Pinealon: A Key Application of Glu-Asp-Arg

A significant area where the glu asp arg peptide is recognized is under the name Pinealon. Pinealon is described as a short synthetic peptide and a pharmaceutical intermediate. It is often presented as a lyophilized powder with high purity, typically exceeding 95%. The development of Pinealon originated in Russia, where it has been studied as part of research into short bioregulatory peptides.

Pinealon, or the EDR peptide, has garnered attention for its potential neuroprotective properties. Research suggests that it may play a role in neuroprotection & brain repair. Studies indicate that Pinealon can epigenetically regulate serotonin synthesis in brain regions like the cortex, which is a crucial neurotransmitter involved in mood regulation and cognitive function. This mechanism is thought to contribute to its observed neuroprotective and antioxidative properties. Furthermore, Pinealon is suggested to prevent the accumulation of reactive oxygen species (ROS), a process implicated in cellular damage and aging.

Scientific Exploration and Related Peptides

The scientific literature details various investigations into the glu asp arg peptide. For instance, one study highlights that Glu-Asp-Arg peptides, alongside others like Lys-Glu-Asp, can epigenetically influence serotonin synthesis. This points to a broader area of research into how short peptides can modulate complex biological processes.

It is important to distinguish Glu-Asp-Arg from other peptide sequences that share some of the same amino acids but have different arrangements or additional amino acids. For example, Asp Arg refers to a specific sequence where Aspartic acid is at the N-terminus and Arginine at the C-terminus, but it does not inherently include Glutamic acid. Similarly, the RGD peptide, which stands for Arg-Gly-Asp, is another well-studied peptide sequence known for its role in cell adhesion and integrin binding. While it contains Arginine and Aspartic acid, its sequence and function differ significantly from Glu-Asp-Arg. The RGD peptide is often used as a tool to study cell attachment and integrin-ligand interactions. Another example is the Ala-Glu-Asp-Gly peptide, a four-amino acid peptide studied for its geroprotective capabilities.

Research and Availability

The glu asp arg peptide, particularly in the form of Pinealon, is primarily supplied for research purposes. It is available from various scientific supply companies, often as a peptide with specified purity levels and quantities, such as 4mg or 20mg. The availability of Pinealon as a white color Pharmaceutical intermediate further underscores its status in scientific research and development.

While the exact price of Pinealon peptide can vary depending on the supplier, quantity, and purity, it is generally considered a specialized research chemical. Discussions around Pinealon peptide price often occur within research communities.

In summary, the glu asp arg peptide is a specific tripeptide composed of glutamic acid, aspartic acid, and arginine. Its most prominent application is under the name Pinealon, a synthetic peptide investigated for its neuroprotective effects and its ability to influence neurotransmitter synthesis. While research continues, the EDR peptide represents a significant area of interest in the field of peptide science.